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  4. Principles of Toxicology Testing 2nd Edition اصول تست سم شناسی
Principles of Toxicology Testing 2nd Edition Taylor & Francis Ltd
Principles of Toxicology Testing 2nd Edition Taylor & Francis Ltd Taylor & Francis Ltd  

Principles of Toxicology Testing 2nd Edition
اصول تست سم شناسی

کد کتاب 186817

Principles of Toxicology Testing 2nd Edition

کتاب اصول تست سم شناسی

افست = اورجینال
چاپ تمام رنگی

کاغذ 80 گرمی اندونزی
جلد سخت و ته دوخت

*بهترین کیفیت افست را از ما بخواهید*

در سطح ملی، برنامه های سم شناسی از اکتشاف سنتی شیمی و سمیت کاربردی مواد شیمیایی و داروها به مطالعه جامع تر سم شناسی و آزمایش سم شناسی به عنوان موجودیت های مستقل تکامل یافته اند. در نتیجه، ویرایش دوم اصول تست سم شناسی با اصول اولیه سم شناسی، از جمله جذب، توزیع، متابولیسم و حذف سموم از جمله مواد شیمیایی و داروها آغاز می شود.

تعداد صفحه
362
چاپ
زبان
سال نشر
شابک
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نوبت چاپ

خرید Principles of Toxicology Testing 2nd Edition

دارای 18% تخفیف  

Principles of Toxicology Testing 2nd Edition

کتاب اصول تست سم شناسی

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development.
As in the first edition, the book begins with an introduction into the fundamentals of toxicology (Section I) to prepare readers for the subsequent topics and continues through with a discussion of toxicokinetics and human risk assessment. This introductory material is useful in understanding the applications of toxicology testing.
Section II describes the fundamental principles of toxicology testing in animals in greater detail. This section describes acute toxicity studies as well as subchronic and chronic studies performed on animals. Special emphasis is placed on study design and determination of classical indicators for acute and chronic testing, such as the LD50. The book examines other short- and long-term animal toxicity testing methodologies, including dermal, ocular, and reproductive toxicity testing. In addition, mutagenicity and carcinogenicity studies are also discussed in separate chapters.
Section III introduces and discusses in vitro alternatives to animal toxicology tests. This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods. They also describe the use of high-throughput screening and its applications, the concepts of standardizatio

Product details

  • Hardback
  • 174 x 246mm | 840g
  • CRC Press
  • London, United Kingdom
  • English
  • New edition
  • 2nd edition
  • 113845706X
  • 9781138457065